In order to resist infectious cancer, the rapid evolution of the devil in Tasmania – Sohu Technology roxane hayward

In order to resist infectious cancer, Tasmania science and technology Sohu – Demon rapid evolution this week "nature – Communication" Rapid evolutionary response to published on a transmissible cancer in Tasmanian devils display, Tasmania demons (Sarcophilus) might have evolved to be known as a devil facial tumor disease (DFTD) invasive cancer resistance. Tasmanian devil is a specialty of Tasmania, australia. This was only the big dog is the biggest current biological surviving marsupial carnivorous animal, because of its black fur, shrill, towering stench, peppery character and predatory behavior is called "the monster of Tasmania". Since 1996, third of the world’s most popular infectious diseases are now known to have been found in animals with a small amount of their own. Tasmanian devil. (source: Save the Tasmanian Devil Program) Sarcophilus disease mortality rate is almost one hundred percent. Because of temper, Sarcophilus often compete for food and mates biting each other. It is generally believed that the epidemic originated from the northeast corner of the island, a female Tasmanian devil, the disease is in the biting process, because cancerous tissue into healthy and infected individuals. The infected badger first produces skin lesions and tumors around the mouth and then spreads to the body. Death from organ failure, secondary infection, or starvation in the course of a few months. In less than 20 years, the deadly disease has reduced the total number of badgers by more than $80%, and scientists are predicting a threat to the threat of the Tasmanian devil. However, it was found that the survival of some of the surviving population was still predicted by the observation of the badger population. In order to find out what makes these devils in disease under the comparison of Andrew Storfer and escape from death in a great catastrophe, colleagues at the Washington State University in three areas Sarcophilus populations in outbreaks before and after the outbreak of multiple point sampling results, the study showed that each region in the 2 and 3 chromosome the allelic variation in disease before and after. Of the 7 genes contained in these regions, there are 5 known and cancer associated with immune function. These genes include genes such as CD146 and THY1 and immune regulation, cancer risk and apoptosis. According to all the data, the Tasmanian devil is facing the DFTD, after more than a decade after 4 to 6 generations of breeding, the rapid evolution of the survival of the Tasmanian devil body has produced the ability to resist DFTD. Australia hare generating process of myxomatosis resistance compared to many generations. The similarities between this study and the dog’s resistance to infectious venereal disease, means there will be a way to understand the evolution of cancer. Future research will focus on the confirmation function of these genes, and the evaluation of different alleles of the survival time of the results after infection相关的主题文章: